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+--- Thread: Risk Factors and Possible Causes of Polymyalgia Rheumatica (/Thread-Risk-Factors-and-Possible-Causes-of-Polymyalgia-Rheumatica)
Risk Factors and Possible Causes of Polymyalgia Rheumatica - KeithD - 10-02-2023
Polymyalgia rheumatica (PMR) is a condition that causes pain and stiffness in the muscles, particularly around the shoulder and hip. While the exact cause of PMR is not known, several factors have been identified as contributing to the development of this condition, including:
- Age: PMR most commonly affects people over the age of 50.
- Gender: Women are more likely to develop PMR than men.
- Genetics: Some evidence suggests that PMR may run in families, indicating a genetic predisposition.
- Chronic inflammation: PMR is associated with chronic low-grade inflammation, and the presence of certain inflammatory markers in the blood has been linked to an increased risk of PMR.
- Other medical conditions: People with other autoimmune diseases, such as rheumatoid arthritis, may be at an increased risk of developing PMR.
- Smoking: Smoking has been linked to an increased risk of PMR and may also worsen the symptoms of the condition.
It's important to note that these factors do not necessarily cause PMR and that the exact cause of this condition remains unknown.